If I were you, I would call up OldmanFCSA and schedule a trip to Osceola no matter where you live to get some training on a Dillon from him. You are a n00b diving into the deep end of the pool with a machine which is going to be doing 4 things at once, and you do not have YEARS of background doing every step on a single station or turret press, so that you know EVERY SINGLE MOVE involved in loading 100.000% safe ammo, and the very real danger you are facing is that something will slip past you because you are NOT used to checking everything out one step at a time. The general concensus in here is if you start out with a Dillon, find tutor who has owned m one and can show you the ropes.
The very real threat you will be facing is the dreaded double charge of a small amount of fast burning powder like Titegroup, Bullseye, or 231, and all three of these are very good powders to use for 45 ACP (and cheap, too!!) so avoiding them isn't the correct response. Something on the machine will jam, you will get distracted, have to manually cycle the system somehow to clear the problem, and somewhere in there you will wind up with a double charge of fast burning powder that WILl blow your 45 apart, and there are no ifs, ands or buts on this. Double charge of fast burning powder equals a KABLOOEY.
So get some training from Oldman on how to use a Dillon safely, or pay the price later... And yes, we have had MULTIPLE people in here ruin 45's with a double charge of powder. (And some 9mm's and 40's too!!)